Since the early 2000s, there has been a rapid
decline in colorectal cancer (CRC) mortality, due in large part
to screening and removal of precancerous polyps. Despite
these improvements, CRC remains the second leading cause
of cancer deaths in the United States, with approximately
53,000 deaths projected...
Evidence-based recommendations on regorafenib (Stivarga) for previously treated metastatic colorectal cancer in adults.
Commercial arrangement
There is a simple discount patient access scheme for regorafenib. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. Non-NHS or...
Kolorektální karcinom je zhoubné onemocnění vycházející z epitelu tlustého střeva a konečníku, pro které je charakteristická vysoká incidence a mortalita ve vyspělých zemích. V civilizovaných zemích patří mezi tři nejčastější karcinomy (mimo karcinom kůže); je třetím nejča...
Pozitronová emisní tomografie (PET) v kombinaci s výpočetní tomografií, popř. s magnetickou rezonancí je zobrazovací vyšetřovací metoda nukleární medicíny. Využívá cíleného funkčního zobrazení specifických vlastností buněk pomocí radiofarmak. Největší uplatnění má PET v s...
This guideline covers managing colorectal (bowel) cancer in people aged 18 and over. It aims to
improve quality of life and survival for adults with colorectal cancer through management of local
disease and secondary tumours (metastatic disease).
The recommendations in this guideline were developed befor...
The COVID-19 pandemic requires to conscientiously weigh ‘‘timely surgical intervention’’ for colorectal cancer against efforts to conserve hospital resources and protect patients and health care providers. Professional societies provided ad-hoc guidance at the outset of the COVID-19 pandemic on d...
This guideline covers managing colorectal (bowel) cancer in people aged 18 and over. It aims to improve quality of life and survival for adults with colorectal cancer through management of local disease and management of secondary tumours (metastatic disease)....
A clinical summary of this KDP was published in the Journal of the Ministry of Health of the Czech Republic. Colorectal carcinoma, a malignancy arising from the epithelium of the colon and rectum, is one of the most common forms of cancer. It is a malignant tumor of global importance and represents one ...
Helsingen, Lise M;
Vandvik, Per Olav;
Jodal, Henriette C;
Agoritsas, Thomas;
Lytvyn, Lyubov;
Anderson, Joseph C;
Auer, Reto;
Murphy, Silje Bjerkelund;
Almadi, Majid Abdulrahman;
Corley, Douglas A;
Quinlan, Casey;
Fuchs, Jonathan M;
McKinnon, Annette;
Qaseem, Amir;
Heen, Anja Fog;
Siemieniuk, Reed A C;
Kalager, Mette;
Usher-Smith, Juliet A;
Lansdorp-Vogelaar, Iris;
Bretthauer, Michael;
Guyatt, Gordon.
Recent 15-year updates of sigmoidoscopy screening trials provide new evidence on the effectiveness of colorectal cancer screening. Prompted by the new evidence, we asked: “Does colorectal cancer screening make an important difference to health outcomes in individuals initiating screening at age 50 to 7...
Generar recomendaciones basadas en la mejor evidencia disponible acerca del manejo de personas
con sospecha o diagnóstico de cáncer de colon o recto....
